Amadeus Arkham was the only son of mentally-ill Elizabeth Arkham, Amadeus watched his mother struggle with her illness for years, which drove him to become a psychiatrist. After her death, he became the sole owner of her home, the Mercey Mansion, which …
Dr. Ricardo Caligari
Hugo Strange was always the smartest and shortest man in the room. He never let either get in his way but his temper always got him into trouble and frequently beaten up by much larger and less capable people, something that enraged him even more.
Dr. Jonathan Crane was first in his class at Harvard, specializing in what makes people afraid and how to overcome those fears. He only wanted one job when he graduated, to work for Arkham Asylum, where the staff deals with Olympic caliber insanity.